Molecular Recognition Tools: Molecular recognition discovery processes developed by the Daugherty group have provided fundamentally new capabilities to create peptides with remarkable specificity for their target(s) while simultaneously accelerating the pace of their discovery.
Antibody Repertoire Analysis: We have developed a new antibody biomarker discovery method that provides the opportunity to discover diagnostically useful biomarkers for unmet medical needs. With clinical collaborators, we are applying these methods to develop reagents suitable for clinical diagnostic development.
Therapeutic Protein Design: We are creating peptide-based probes that enable quantitative measurements of protease activity in living organisms. In particular we are constructing novel activity-based molecular probes to elucidate the functions of proteases involved in cancer progression.