I am exploring the use of LOV (light-, oxygen-, voltage-sensing) fluorescent proteins as scaffolds to build genetically encodable biosensors to visualize cellular chemicals (e.g. ATP, cyclic AMP, protease) in low-oxygen environments. Such biosensors are promising tools for studying the cell biology of anaerobes that are previously not well-understood using traditional green fluorescent proteins (GFPs).
I came from Taipei, Taiwan, and graduated from National Taiwan University (NTU) in 2015 with a BS in Chemical Engineering. During college, I studied the thermophoresis phenomenon of lipid molecules using supported lipid bilayer (SLB) as a platform. Outside of the lab, I enjoy hiking, biking, playing the piano, and cooking.
Tools and Techniques: protein engineering, fluorescence microscopy, fluorescence-activated cell sorting (FACS), fluorescence recovery after photobleaching (FRAP), imaging processing, microfluidics